Adoptive immunotherapy of cancer with activated lymph node cells primed in vivo with autologous tumor cells transduced with the GM-CSF gene

Hum Gene Ther. 1996 Apr 10;7(6):773-92. doi: 10.1089/hum.1996.7.6-773.
No abstract available

Publication types

  • Clinical Trial

MeSH terms

  • Animals
  • Antibodies, Monoclonal / immunology
  • Cancer Vaccines / administration & dosage
  • Cancer Vaccines / genetics
  • Cancer Vaccines / immunology
  • Clinical Protocols
  • Feasibility Studies
  • Gene Transfer Techniques
  • Genetic Vectors
  • Granulocyte-Macrophage Colony-Stimulating Factor / genetics*
  • Granulocyte-Macrophage Colony-Stimulating Factor / metabolism
  • Humans
  • Immunotherapy, Adoptive*
  • Interleukin-2 / administration & dosage
  • Kidney Neoplasms / genetics
  • Kidney Neoplasms / immunology
  • Kidney Neoplasms / therapy*
  • Lymph Nodes / cytology*
  • Lymphocyte Activation
  • Melanoma / genetics
  • Melanoma / immunology
  • Melanoma / therapy*
  • Moloney murine leukemia virus / genetics
  • T-Lymphocytes / immunology
  • T-Lymphocytes / transplantation*
  • Tumor Cells, Cultured / immunology

Substances

  • Antibodies, Monoclonal
  • Cancer Vaccines
  • Interleukin-2
  • Granulocyte-Macrophage Colony-Stimulating Factor