Primary infection by HHV-6 variant B associated with a fatal case of hemophagocytic syndrome

M Portolani; C Cermelli; M Meacci; P Pietrosemoli; M Pecorari; A M Sabbatini; S Leoni; A Guerra; G Bonaccorsi

Primary infection by HHV-6 variant B associated with a fatal case of hemophagocytic syndrome

New Microbiol. 1997 Jan;20(1):7-11.

Authors

M Portolani¹, C Cermelli, M Meacci, P Pietrosemoli, M Pecorari, A M Sabbatini, S Leoni, A Guerra, G Bonaccorsi

Affiliation

¹ Department of Biomedical Sciences, University of Modena, Italy.

PMID: 9037663

Abstract

The association of a human herpesvirus 6 primary infection with a fatal case of hemophagocytic syndrome in a 3 month old baby is described. The trigger mechanism of the virus for the clinical syndrome is discussed.

Publication types

Case Reports

MeSH terms

Animals
Antibodies, Viral / analysis
Cells, Cultured
Chlorocebus aethiops
DNA, Viral / analysis
Enzyme-Linked Immunosorbent Assay
Female
Fibroblasts
Herpesviridae / immunology
Herpesvirus 6, Human / genetics
Herpesvirus 6, Human / immunology
Herpesvirus 6, Human / isolation & purification*
Histiocytosis, Non-Langerhans-Cell / cerebrospinal fluid
Histiocytosis, Non-Langerhans-Cell / diagnosis*
Humans
Immunoglobulin G / analysis
Immunoglobulin M / analysis
Infant
Polymerase Chain Reaction
Vero Cells

Substances

Antibodies, Viral
DNA, Viral
Immunoglobulin G
Immunoglobulin M