3D gadolinium-enhanced MR angiography of the carotid arteries

Magn Reson Imaging. 1996;14(6):593-600. doi: 10.1016/0730-725x(96)00091-4.

Abstract

Purpose: To compare gadolinium-enhanced magnetic resonance angiography (MRA) of the carotid bifurcation with 2D time-of-flight (TOF) MR angiography with regard to image quality and duration of examination.

Materials and methods: Gadolinium contrast was administered intravenously during 3D MR imaging at 1.5 Tesla in 46 patients presenting with suspected carotid occlusive disease. 2D time-of-flight MR angiography of the carotid bifurcation had been performed in each patient prior to gadolinium-enhanced MR angiography.

Results: Gadolinium MRA eliminated slice misregistration and in-plane saturation artifacts that occasionally degrades 2D TOF MR angiography. Gadolinium MRA required less than 4 min to image from the aortic arch to the skull base compared to 11 min for 2D TOF with comparable signal-to-noise ratio (SNR). Postprocessing was required to eliminate overlapping venous enhancement. Both techniques had susceptibility related artifactual loss of signal at the skull base and both demonstrated a linear artifact paralleling the long axis of arteries.

Conclusion: Gadolinium-enhanced MR angiography is a promising technique for the evaluation of patients with carotid occlusive disease because it rapidly images the carotid arteries from the aortic arch to the skull base and eliminates some of the artifacts that degrade 2D TOF MR angiography.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Carotid Arteries / pathology*
  • Carotid Stenosis / diagnosis*
  • Contrast Media*
  • Drug Combinations
  • Female
  • Gadolinium DTPA
  • Gadolinium*
  • Humans
  • Image Processing, Computer-Assisted
  • Magnetic Resonance Angiography*
  • Male
  • Meglumine
  • Middle Aged
  • Organometallic Compounds
  • Pentetic Acid / analogs & derivatives

Substances

  • Contrast Media
  • Drug Combinations
  • Organometallic Compounds
  • Meglumine
  • Pentetic Acid
  • Gadolinium
  • Gadolinium DTPA