Probable risk of tumour induction after retro-orbital irradiation for Graves' ophthalmopathy

Radiother Oncol. 1996 Jan;38(1):69-71. doi: 10.1016/0167-8140(95)01670-8.

Abstract

Retrobulbar irradiation for Graves' ophthalmopathy is considered as a safe treatment and has recently been recommended as the initial treatment for patients with moderately severe eye problems. However, calculations using risk factors presently known reveal a theoretical risk of radiation-induced cancer of 1.2%. Therefore, the authors suggest that this treatment should be reserved for the elderly patient, for example above the age of 40-50 years.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Age Factors
  • Eye Diseases / radiotherapy*
  • Female
  • Graves Disease / radiotherapy*
  • Humans
  • Monte Carlo Method
  • Neoplasms, Radiation-Induced / etiology*
  • Phantoms, Imaging
  • Probability
  • Radiotherapy Dosage
  • Radiotherapy, High-Energy / adverse effects
  • Risk Factors
  • Safety