[Effects of three kinds of decoction on histopathology of gastric mucosa, gastric pH and the content of bile acid in experimental chronic gastritis in rats]

Zhongguo Zhong Yao Za Zhi. 1995 Aug;20(8):488-92, inside backcover.
[Article in Chinese]

Abstract

Experimental chronic gastritis (ECG) models were established in rats by inserting a spring into pyloric canal as well as feeding sodium deoxycholate. An experiment was undertaken to observe the therapeutic effects of three formulas of traditional Chinese medicine "Shipitong", "Ganpingyangwei" and "Weile". The experimental results show that all of the three decoctions can reduce gastric pH and bile acid of the ECG rats and make gastric mucosal histomorphology of these rats change markedly.

MeSH terms

  • Animals
  • Bile Acids and Salts / metabolism*
  • Chronic Disease
  • Drugs, Chinese Herbal / therapeutic use*
  • Gastric Acid / metabolism*
  • Gastric Mucosa / pathology*
  • Gastritis / drug therapy*
  • Gastritis / metabolism
  • Gastritis / pathology
  • Gastrointestinal Agents / therapeutic use*
  • Hydrogen-Ion Concentration
  • Male
  • Rats
  • Rats, Wistar

Substances

  • Bile Acids and Salts
  • Drugs, Chinese Herbal
  • Gastrointestinal Agents