Identification of markers flanking the tuberous sclerosis locus on chromosome 9 (TSC1)

J Med Genet. 1993 Mar;30(3):224-7. doi: 10.1136/jmg.30.3.224.

Abstract

Analysis of a large tuberous sclerosis pedigree confirmed linkage to a locus on the long arm of chromosome 9, with recombination events placing the disease gene distal to gelsolin and proximal to dopamine beta-hydroxylase.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • ABO Blood-Group System / genetics
  • Calcium-Binding Proteins / genetics
  • Chromosome Mapping
  • Chromosomes, Human, Pair 9*
  • Dopamine beta-Hydroxylase / genetics
  • Female
  • Gelsolin
  • Genetic Linkage*
  • Genetic Markers
  • Haplotypes
  • Humans
  • Male
  • Microfilament Proteins / genetics
  • Pedigree
  • Polymorphism, Genetic
  • Recombination, Genetic
  • Tuberous Sclerosis / genetics*

Substances

  • ABO Blood-Group System
  • Calcium-Binding Proteins
  • Gelsolin
  • Genetic Markers
  • Microfilament Proteins
  • Dopamine beta-Hydroxylase