Linkage analysis in familial Alzheimer disease: description of the Duke and Boston data sets

M A Pericak-Vance; P H St George-Hyslop; P C Gaskell Jr; J Growdon; B J Crain; C Hulette; J F Gusella; L Yamaoka; R E Tanzi; A D Roses

doi:10.1002/gepi.1370100605

Linkage analysis in familial Alzheimer disease: description of the Duke and Boston data sets

Genet Epidemiol. 1993;10(6):361-4. doi: 10.1002/gepi.1370100605.

Authors

M A Pericak-Vance¹, P H St George-Hyslop, P C Gaskell Jr, J Growdon, B J Crain, C Hulette, J F Gusella, L Yamaoka, R E Tanzi, A D Roses, et al.

Affiliation

¹ Division of Neurology, Duke University Medical Center, Durham, NC 27710.

PMID: 8314027
DOI: 10.1002/gepi.1370100605

Abstract

Familial Alzheimer diseases is a neurological disorder of adult onset. Three research centers have each contributed their families and genetic linkage data for combined analyses. The data from the Duke and Boston centers, comprising 73 pedigrees for whom numerous markers on chromosomes 19 and 21 were typed are described.

Publication types

Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, P.H.S.
Review

MeSH terms

Aged
Alzheimer Disease / epidemiology
Alzheimer Disease / genetics*
Boston / epidemiology
Chromosomes, Human, Pair 19
Chromosomes, Human, Pair 21
Genetic Linkage*
Genetic Markers
Humans
Middle Aged
North Carolina / epidemiology
Pedigree

Substances

Genetic Markers

Grants and funding

etc