Preparation and properties of buserelin suspensions

Boll Chim Farm. 1994 Mar;133(3):156-9.

Abstract

Obtaining and some properties of suspensions with buserelin-there were obtained buserelin suspensions with zinc ions with pH 7.2-7.5 and hormone: zinc molar ratio from 1:2.5 to 1:500. The obtained buserelin suspensions show moderated hormone release in vitro and prolonged action in vivo. The pulsating buserelin release from suspensions has been found in vitro and in vivo.

MeSH terms

  • Animals
  • Buserelin / administration & dosage*
  • Buserelin / chemistry
  • Buserelin / pharmacokinetics
  • Chemical Phenomena
  • Chemistry, Physical
  • Injections, Intramuscular
  • Suspensions
  • Swine

Substances

  • Suspensions
  • Buserelin