Background: Cystosarcoma phyllodes is a rare mesenchymal tumor in the breast with a quite different prognosis depending on its specific dignity. There are almost no data in the literature concerning therapeutic strategies of metastasized cystosarcoma phyllodes.
Patients and methods: We report the unique case of a young female patient with advanced multiple liver metastases of a cystosarcoma phyllodes malignum.
Results: After irradiation of the total liver combined with simultaneous chemotherapy containing ifosfamide and adriamycin an impressing 12 months lasting remission and control of the liver metastases was achieved. No relevant treatment side effects were observed.
Conclusion: Combined liver irradiation and simultaneous chemotherapy should be considered as effective treatment strategy for comparable situations in young patients with good physical conditions.