[Establishment of mouse model for Cysticercosis cellulosae]

Zhongguo Ji Sheng Chong Xue Yu Ji Sheng Chong Bing Za Zhi. 1994;12(4):297-9.
[Article in Chinese]

Abstract

Sixty mice were inoculated intravenously with 200-400 Taenia solium eggs collected from the gravid proglottides of the adult worm expelled from a taeniasis patient after pumpkin seed and areca treatment. The mice were killed and dissected 2 months after inoculation, and were found infected with Cysticercus cellulosae. These living cysticerci in muscles and lungs were elliptic in shape with diameters of 0.3-0.6 cm. The scolex was equipped with two rows of hooks and four typical suckers. When the cysticerci were hatched in gastric juice and bile for two hours at 37 degrees C the scoleces evaginated voluntarily. The results of this study suggest that the mouse can be used as an animal model for Cysticercus cellulosae.

Publication types

  • English Abstract

MeSH terms

  • Animals
  • Cricetinae
  • Cysticercosis*
  • Disease Models, Animal*
  • Female
  • Guinea Pigs
  • Male
  • Mice
  • Rats