In the patients with bronchial asthma, the chemiluminescence (CL) of polymorphonuclear (PMN) and lymphocyte (LY) in blood had two peaks, maximal peak value decreased and peak time prolonged: cAMP, cAMP/cGMP, SOD in plasma decreased, IgE increased. The authors suggest that the pathogenetic mechanism of bronchial asthma may related to activated inflammatory cells, released mediators and inbalanced immuno opsonic functions.