1,628 myopic eyes were performed with excimer laser photorefractive keratectomy (PRK) and 1% prednisolon eyedrops was used for postoperative regime. All patients after PRK were followed 2-14 months, 9.89% had an intraocular pressure of more than 2.933 kPa (22mmHg) at first month and 15.05% at third month. Male patients showed higher response to glucocorticoid than female patients. There was no correlation between elevations of intraocular pressue and refractive powers.