[Effects of 3 kinds of decoction on serum gastrin, gastrin cell density and the content of PGE2 of gastric antral mucosa in experimental chronic gastritis in rats]

Zhongguo Zhong Yao Za Zhi. 1995 Jun;20(6):361-4, 384.
[Article in Chinese]

Abstract

Experimental chronic gastritis (ECG) models were established in rats by inserting a spring into pyloric canal as well as feeding sodium deoxycholate. An experiment was undertaken to observe the therapeutic effects of three formulas of traditional Chinese medicine "Shipitong" (SPT), "Ganpingyangwei" (GPYW) and "Weile" (WL). The experimental results show that all of the three decoctions can make serum gastrin, gastrin cell density and amount of antral mucosal PGE2 of the ECG rats return to normal levels.

Publication types

  • English Abstract
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Cell Count
  • Chronic Disease
  • Dinoprostone / metabolism*
  • Drug Combinations
  • Drugs, Chinese Herbal / therapeutic use*
  • Gastric Mucosa / chemistry*
  • Gastric Mucosa / pathology
  • Gastrins / blood*
  • Gastritis / drug therapy*
  • Gastritis / metabolism
  • Male
  • Rats
  • Rats, Wistar

Substances

  • Drug Combinations
  • Drugs, Chinese Herbal
  • Gastrins
  • Dinoprostone