Unusual clinical manifestation of a disfiguring necrobiotic granulomatous disease

J Am Acad Dermatol. 1995 Nov;33(5 Pt 2):887-90. doi: 10.1016/0190-9622(95)90429-8.

Abstract

A 39-year-old woman had a disfiguring granulomatous disease of 36 years' duration. Nodules appeared on her lower extremities and later extended to her face; this led to ulceration and destruction of the nasal cartilage. This disease of unknown origin does not conform to any previously described entity. Some patients with a similar case presentation have been observed in France.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Adult
  • Biopsy
  • CD4-CD8 Ratio
  • Female
  • Granulomatous Disease, Chronic / diagnosis*
  • Granulomatous Disease, Chronic / drug therapy
  • Granulomatous Disease, Chronic / immunology
  • Humans
  • Leg
  • Nasal Septum
  • Necrobiotic Disorders / diagnosis*
  • Necrobiotic Disorders / drug therapy
  • Necrobiotic Disorders / immunology
  • Nose
  • Skin / microbiology
  • Skin / pathology