Interval mammography after needle localization biopsy of breast abnormalities that are pathologically benign

Am J Surg. 1995 Oct;170(4):323-6. doi: 10.1016/s0002-9610(99)80297-9.

Abstract

Background: Needle localization biopsy is commonly performed for the diagnosis of mammographic abnormalities. Routine specimen radiography is generally recommended, but the value of routine short-interval postbiopsy mammography has not been analyzed.

Patients and methods: We performed a retrospective review of 299 consecutive localized biopsies in 286 women from March 1989 to November 1993. Of these biopsies, 217 from the basis for this study; all yielded a benign pathologic diagnosis and had both specimen radiography and 3-month interval mammograms performed.

Results: A total of 192 (88%) of postbiopsy mammograms were interpreted as negative, while 22 (10%) were suspicious. Three patients had second biopsies and all had benign diagnoses, 16 had follow-up mammograms that were interpreted as normal or stable, and 3 patients were lost to follow-up. A suspicious postbiopsy mammogram had no significant relationship to initial mammographic abnormality or pathologic diagnosis, but did correlate with specimen radiograph interpretation (P = 0.02) by chi-square comparison).

Conclusions: In a series of needle localization biopsies with intraoperative specimen radiography, postbiopsy mammography failed to reveal any missed cancers. Short-interval follow-up mammography is unnecessary to assess for residual abnormalities when specimen radiography confirms excision of the abnormality.

MeSH terms

  • Biopsy, Needle
  • Breast Neoplasms / diagnostic imaging*
  • Breast Neoplasms / pathology*
  • Female
  • Humans
  • Intraoperative Period
  • Mammography*
  • Predictive Value of Tests
  • Retrospective Studies
  • Sensitivity and Specificity
  • Time Factors