Biosynthesis of pregnenolone from cholesterol by mitochondrial enzymes of bovine adrenal cortex. The question of the participation of the 20(22)-olefins and 20, 22-epoxides of cholesterol

Eur J Biochem. 1978 Nov 2;91(1):11-9. doi: 10.1111/j.1432-1033.1978.tb20931.x.
No abstract available

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Adrenal Cortex / enzymology*
  • Animals
  • Cattle
  • Cholesterol / analogs & derivatives
  • Cholesterol / metabolism*
  • Cholesterol Side-Chain Cleavage Enzyme / metabolism
  • Cytochrome P-450 Enzyme System / metabolism
  • Epoxy Compounds / metabolism*
  • Ethers, Cyclic / metabolism*
  • Mitochondria / enzymology*
  • Pregnenolone / biosynthesis*
  • Radioimmunoassay
  • Steroids / metabolism
  • Structure-Activity Relationship

Substances

  • Epoxy Compounds
  • Ethers, Cyclic
  • Steroids
  • Pregnenolone
  • Cytochrome P-450 Enzyme System
  • Cholesterol
  • Cholesterol Side-Chain Cleavage Enzyme