Liver as a tumor-cell-killing organ

Immunol Commun. 1984;13(1):77-81. doi: 10.3109/08820138409025451.

Abstract

Lymphoma cells (Eb and ESb, the metastasizing variant) were injected via a mesenteric vein. 85% to 95% of these cells were trapped in the liver. Most of the Eb cells (81%) were destroyed within 18 hours, ESb cells prove to be more resistant: only 28% of these cells were destroyed within this time. 51-Chromium release assay (4 hours) revealed a similar sensitivity of these two tumor cell strains.

Publication types

  • Comparative Study

MeSH terms

  • Animals
  • Cytotoxicity, Immunologic
  • Female
  • Killer Cells, Natural / immunology*
  • Liver / immunology*
  • Lymphoma / metabolism*
  • Mice
  • Mice, Inbred DBA
  • Neoplasm Metastasis
  • Rats
  • Rats, Inbred Strains