[Sympathetic paraganglioma. Scintigraphic detection using a new labeled molecule, meta-iodobenzylguanidine]

Presse Med. 1984 Jun 30;13(27):1679-82.
[Article in French]

Abstract

Two cases of sympathetic paraganglioma are reported: one, benign, in a 20-years old woman with arterial hypertension and attacks of excessive sweating; the other, malignant and with bone metastases, in a 44-years old woman. Both were diagnosed by scintigraphy, using meta-iodobenzylguanidine as radionuclide. This new radiopharmaceutic agent has recently been introduced for the detection of phaeochromocytomas, but it seems to be a general tissue marker of catecholamine uptake and storage. Its use as a therapeutic compound may also be envisaged.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • 3-Iodobenzylguanidine
  • Abdominal Neoplasms / diagnostic imaging
  • Adrenal Gland Neoplasms / diagnostic imaging
  • Adult
  • Bone Neoplasms / diagnostic imaging
  • Bone Neoplasms / secondary
  • Bone and Bones / diagnostic imaging
  • Catecholamines / metabolism
  • Female
  • Ganglia, Sympathetic
  • Humans
  • Iodine Radioisotopes
  • Iodobenzenes*
  • Paraganglioma / diagnostic imaging*
  • Paraganglioma / secondary
  • Pheochromocytoma / diagnostic imaging
  • Radionuclide Imaging
  • Sympatholytics*

Substances

  • Catecholamines
  • Iodine Radioisotopes
  • Iodobenzenes
  • Sympatholytics
  • 3-Iodobenzylguanidine