Abstract
Two cases of sympathetic paraganglioma are reported: one, benign, in a 20-years old woman with arterial hypertension and attacks of excessive sweating; the other, malignant and with bone metastases, in a 44-years old woman. Both were diagnosed by scintigraphy, using meta-iodobenzylguanidine as radionuclide. This new radiopharmaceutic agent has recently been introduced for the detection of phaeochromocytomas, but it seems to be a general tissue marker of catecholamine uptake and storage. Its use as a therapeutic compound may also be envisaged.
Publication types
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Case Reports
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Research Support, Non-U.S. Gov't
MeSH terms
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3-Iodobenzylguanidine
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Abdominal Neoplasms / diagnostic imaging
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Adrenal Gland Neoplasms / diagnostic imaging
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Adult
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Bone Neoplasms / diagnostic imaging
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Bone Neoplasms / secondary
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Bone and Bones / diagnostic imaging
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Catecholamines / metabolism
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Female
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Ganglia, Sympathetic
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Humans
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Iodine Radioisotopes
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Iodobenzenes*
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Paraganglioma / diagnostic imaging*
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Paraganglioma / secondary
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Pheochromocytoma / diagnostic imaging
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Radionuclide Imaging
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Sympatholytics*
Substances
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Catecholamines
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Iodine Radioisotopes
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Iodobenzenes
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Sympatholytics
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3-Iodobenzylguanidine