Synergistic photocatalysis enables aerobic oxo-hydrazination of α-diazoacetates with azobenzenes

Chem Commun (Camb). 2024 Dec 18. doi: 10.1039/d4cc05668j. Online ahead of print.

Abstract

A photocatalytic oxo-hydrazination of α-diazoacetates with azobenzenes has been developed. With air as an oxygen source, the reaction proceeded smoothly and afforded previously unknown N,N'-diarylhydrazino-containing oxoacetates. Mechanistically, the reaction is enabled by cooperation of photoredox catalysis, energy transfer photocatalysis and direct photoexcitation.