Fertilization and evolution: AI-powered search finds a missing link in sperm-egg interaction

Xiaofang Huang; Jean-Ju Chung

doi:10.1016/j.cub.2024.10.051

Fertilization and evolution: AI-powered search finds a missing link in sperm-egg interaction

Curr Biol. 2024 Dec 2;34(23):R1169-R1172. doi: 10.1016/j.cub.2024.10.051.

Authors

Xiaofang Huang¹, Jean-Ju Chung²

Affiliations

¹ Department of Cellular and Molecular Physiology, Yale University School of Medicine, New Haven, CT, USA.
² Department of Cellular and Molecular Physiology, Yale University School of Medicine, New Haven, CT, USA; Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, New Haven, CT, USA. Electronic address: jean-ju.chung@yale.edu.

PMID: 39626626
DOI: 10.1016/j.cub.2024.10.051

Abstract

Fertilization starts life, yet the details of sperm-egg binding and fusion remain mysterious. A recent study sheds new light on this intricate process, offering key insights into its molecular workings and evolutionary significance.

MeSH terms

Animals
Biological Evolution*
Female
Fertilization* / physiology
Male
Sperm-Ovum Interactions* / physiology
Spermatozoa / physiology