Clinical value of capsule endoscopy, CT enterography and enteroscopy in the diagnosis of suspected small bowel bleeding

Yiling Xiong; Ruiri Jin; Sheng Chen; Xingxing Liu; Zhenyu Wu; Die Zhang; Chunyan Zeng; Youxiang Chen

doi:10.1007/s00464-024-11405-6

Clinical value of capsule endoscopy, CT enterography and enteroscopy in the diagnosis of suspected small bowel bleeding

Surg Endosc. 2024 Nov 22. doi: 10.1007/s00464-024-11405-6. Online ahead of print.

Authors

Yiling Xiong^#¹, Ruiri Jin^#¹, Sheng Chen¹, Xingxing Liu¹, Zhenyu Wu¹, Die Zhang¹, Chunyan Zeng², Youxiang Chen³

Affiliations

¹ Jiangxi Provincial Key Laboratory of Digestive Diseases, Department of Gastroenterology, Jiangxi Clinical Research Center for Gastroenterology, Digestive Disease Hospital, The First Affiliated Hospital, Jiangxi Medical College, Nanchang University, 17 Yongwaizheng Street, Nanchang, 330006, Jiangxi, China.
² Department of Gastroenterology, Jiangxi Province Hospital of Integrated Chinese and Western Medicine, 90 Bayi Road, Xihu, Nanchang, Jiangxi, China. zengcy896@ncu.edu.cn.
³ Jiangxi Provincial Key Laboratory of Digestive Diseases, Department of Gastroenterology, Jiangxi Clinical Research Center for Gastroenterology, Digestive Disease Hospital, The First Affiliated Hospital, Jiangxi Medical College, Nanchang University, 17 Yongwaizheng Street, Nanchang, 330006, Jiangxi, China. chenyx102@ncu.edu.cn.

^# Contributed equally.

PMID: 39578291
DOI: 10.1007/s00464-024-11405-6

Abstract

Background: Fewer studies have been conducted on the diagnostic value of capsule endoscopy, CT enterography and enteroscopy in suspected small bowel bleeding. This study aimed at analyzing the diagnostic and clinical value of capsule endoscopy, CT enterography and enteroscopy for suspected small bowel bleeding.

Methods: This retrospective study compared the diagnostic rate and consistency of findings among groups. In addition, diagnostic rates were compared between combined enteroscopy versus uncombined enteroscopy associated with capsule endoscopy or CT enterography, as well as the influencing factors of diagnostic outcomes. The complete enteroscopy rates and diagnostic rates were analyzed for the one-day enteroscopy group and the non-one-day enteroscopy group.

Results: There was no significant difference in diagnostic rates between capsule endoscopy (n = 70) and CT enterography (n = 122) (χ² = 3.334; p = 0.068), while the diagnostic rate of enteroscopy (n = 396) is higher than capsule endoscopy (χ² = 10.064; p = 0.002) and CT enterography (χ² = 42.661; p < 0.001). Diagnostic rates were much higher in patients with a successful completion of docking inspection (n = 64) than in undocked patients (n = 60) (85.9% vs 46.7%; p < 0.001), even though these patients still had combined capsule endoscopy or CT enterography. The complete enteroscopy rates (χ² = 0.364; P = 0.546) and diagnostic rates (χ² = 2.511; P = 0.113) of enteroscopy in the one-day group (n = 55) were not significantly different from those in the non-one-day group (n = 25).

Conclusions: Enteroscopy is the more reliable method of diagnosing suspected small bowel bleeding among enteroscopy, capsule endoscopy and CT enterography. Moreover, uncompleted enteroscopy combined with capsule endoscopy or CT enterography may not yet be a substitute for successful completion of docking enteroscopy in clinical practice.

Keywords: CT enterography; Capsule endoscopy; Enteroscopy; Small bowel bleeding.

Abstract

Grants and funding