Characterisation of ginsenosides composition in processed American ginseng products using UPLC-MS coupled with chemometric analysis

Nat Prod Res. 2024 Nov 22:1-5. doi: 10.1080/14786419.2024.2431127. Online ahead of print.

Abstract

American ginseng(Panax quinquefolius L.), a traditional herbal extensively utilised in China, exhibits both medicinal and food properties. Diverse processing American ginseng gain extensive utilisation in China. In this study, we used to UPLC-Q-Orbitrap-MS to identify the compositions of diverse processed products of American ginseng, resulting in the identification of a total of 49 compounds. The utilisation of 18 of these ingredients enables the discrimination among diverse processed forms of American ginseng. The application of chemometric reveals notable disparities in the chemical compositions among various processed products. The result showed that chemical composition combined with chemometric is effectively and accurately to identify diverse American ginseng prepared products.

Keywords: American ginseng; ginsengoside; multivariate statistical analysis; orbitrap mass spectrometry.