Background: A novel lattice tip ablation catheter that can toggle between radiofrequency and pulsed-field energy is able to perform not only pulmonary vein isolation, but also linear lesions under general anesthesia (GA).
Objective: We aimed to evaluate the concerns associated with the use of deep sedation and the clinical data related to linear ablation.
Methods: Clinical data from two Germany high-volume atrial fibrillation (AF) centers were collected. The objectives of this study are to confirm the feasibility and safety of linear lesion ablation using the lattice tip catheter without GA. Acute procedural and short-term follow-up data were collected.
Results: This study included 55 patients who underwent AF ablation (15 with GA versus 40 with deep sedation) including linear lesion ablation for atrial tachyarrhythmia using a lattice tip catheter. Bidirectional block of linear lesions was achieved in 21/21 linear lesions in the GA and in 74/76 (97%) linear lesions in the deep sedation group (P=1.000) including: roof line in 41/41 (100%), posterior wall isolation in 4/4 (100%), anterior mitral isthmus (MI) line in 5/5 (100%) versus 24/25 (96%), posterior MI line in 1/1 (100%) versus 4/5 (80%), cavo-tricuspid isthmus line in 15/15 (100%), and one left atrial appendage isolation. The overall incidence rate of complications was 1.8% (one cardiac tamponade). There was no other procedural related complication.
Conclusion: This preliminary clinical study demonstrates feasibility and safety of bidirectional block of linear lesions using a lattice tip catheter under deep sedation. Need to toggle between energy sources was low.
Keywords: atrial fibrillation; deep sedation; lattice tip catheter; linear ablation; pulsed-field ablation.
Copyright © 2024. Published by Elsevier Inc.