Regioselective functionalization of cellulose nanomaterial for advanced application

Qianqian Wang; Lin Zhong; Yang Zhou; Shixuan Feng; Jun Liu; Huan Liu; Qianqian Zhu

doi:10.1016/j.carbpol.2024.122889

Regioselective functionalization of cellulose nanomaterial for advanced application

Carbohydr Polym. 2025 Jan 15;348(Pt B):122889. doi: 10.1016/j.carbpol.2024.122889. Epub 2024 Oct 18.

Authors

Qianqian Wang¹, Lin Zhong², Yang Zhou², Shixuan Feng², Jun Liu², Huan Liu², Qianqian Zhu³

Affiliations

¹ Biofuels Institute, School of the Environment and Safety Engineering, School of Emergency Management, Jiangsu University, Zhenjiang 212013, China; Jiangsu Collaborative Innovation Center of Technology and Material of Water Treatment, Suzhou University of Science and Technology, Suzhou 215009, China; Multidimensional Spectral Traceability Monitoring Technology and Equipment Anhui Engineering Research Center, Hefei, Anhui 230051, China. Electronic address: wqq@ujs.edu.cn.
² Biofuels Institute, School of the Environment and Safety Engineering, School of Emergency Management, Jiangsu University, Zhenjiang 212013, China.
³ Biofuels Institute, School of the Environment and Safety Engineering, School of Emergency Management, Jiangsu University, Zhenjiang 212013, China; Institute of Quantum and Sustainable Technology (IQST), School of Chemistry and Chemical Engineering, Jiangsu University, Zhenjiang, Jiangsu 212013, China; Analysis and Testing Center, Jiangsu University, Zhenjiang 212013, China. Electronic address: happzqq@ujs.edu.cn.

PMID: 39567165
DOI: 10.1016/j.carbpol.2024.122889

Abstract

Cellulose nanomaterials (CNMs) with their remarkable properties and abundant natural sources have emerged as a versatile platform for material science. However, their widespread adoption to develop novel applications often hinges on precise control over their surface chemistry. Regioselective functionalization, i.e., the ability to modify specific hydroxy groups on the cellulose backbone or aldehyde reducing end group (REG), offers unparalleled control on their surface chemistry. This review highlights the exciting developments in regioselective functionalization of CNMs and their impacts on structure-property relationships. Key factors that influence regioselectivity are examined and exciting applications of regioselectively functionalized CNMs are reviewed. This review also highlights the need for efficient, large-scale regioselective functionalization techniques and identifies key areas for future research.

Keywords: Application; Cellulose nanomaterial; Regioselective modification; Structure-property; Surface chemistry.

Publication types

Review