Unilateral Virginal Breast Hypertrophy: A Report of a Rare Condition With an Unknown Etiology

Cureus. 2024 Oct 18;16(10):e71809. doi: 10.7759/cureus.71809. eCollection 2024 Oct.

Abstract

Unilateral virginal hypertrophy of the breast is a rare condition with an unknown etiology, though it is thought to result from hypersensitivity of the end organs to normal levels of gonadal hormones. We present the case of a 17-year-old girl who initially showed gradual growth after thelarche; however, in the last three to four months, there was a rapid increase in size, leading to psychological and physical problems that also impacted her social life. A clinical examination revealed that her left breast was markedly enlarged compared to the right, and she exhibited a drooping posture. Radiological investigations and a true-cut biopsy were performed to detect any underlying pathology, which revealed normocellular stroma consistent with virginal breast hypertrophy.

Keywords: abnormal breast development; benign breast condition; breast disease; breast reduction surgery (brs); giant fibroadenoma; gigantomastia; macromastia; unilateral virginal hypertrophy.

Publication types

  • Case Reports