Facial nerve palsy (FNP) may arise from multiple etiological reasons, including anatomical anomalies, circulatory complications, and infectious agents. This case series underscores the importance of a comprehensive diagnostic approach to identify the precise etiology, including structural abnormalities, vascular anomalies, or infectious illnesses. Here, we present three distinct occurrences of FNP, emphasizing the varied diagnostic difficulties and therapeutic strategies. It includes an arachnoid cyst, which when occurring at the cerebellopontine angle can affect multiple cranial nerves, specifically the seventh and eighth cranial nerve, a neurovascular compression syndrome, where the anterior inferior cerebellar artery loops around the facial nerve. Most often, this scenario causes hemifacial spasms, which in our scenario manifests as FNP. Lyme disease is a tick-borne disease that affects multiple cranial nerves, specifically the facial nerve. Effective management necessitates a focused treatment strategy that tackles the symptoms and the underlying disease. Advanced imaging techniques, serological tests, and a tailored treatment approach are essential for effective diagnosis, can have significant implications for patient well-being, and necessitate a thorough evaluation to identify underlying causes. This case series illustrates the diverse etiologies of FNP, emphasizing the need for comprehensive diagnostic strategies and targeted treatments. As clinicians encounter FNPs more often, this case series can help physicians understand facial palsy better. Continuous research and clinical awareness are vital for improving patient outcomes in cases of FNP.
Keywords: arachnoid cyst; lyme disease; seventh cranial nerve palsy; unilateral facial nerve palsy; vascular loop compression.
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