2 Heart Institute, Hospital das Clinicas HCFMUSP, Universidade de São Paulo, São Paulo, Brazil. otavio.ranzani@isglobal.org.
3 General ICU, Sepsis Comprehensive Center, Laboratory of Inflammation and Infection U1173 INSERM, Raymond Poincaré Hospital (APHP), IHU PROMETHEUS, University of Paris Saclay UVSQ, Garches, France.
4 Bloomsbury Institute of Intensive Care Medicine, Division of Medicine, University College London, London, UK.