Advancing extracorporeal carbon dioxide removal technology: bridging basic science and clinical practice

Sergio Lassola; Denise Battaglini; Silvia De Rosa

doi:10.4103/mgr.MEDGASRES-D-24-00051

Advancing extracorporeal carbon dioxide removal technology: bridging basic science and clinical practice

Med Gas Res. 2024 Nov 8. doi: 10.4103/mgr.MEDGASRES-D-24-00051. Online ahead of print.

Authors

Sergio Lassola¹, Denise Battaglini^{2

3}, Silvia De Rosa^{1

4}

Affiliations

¹ Anesthesia and Intensive Care, Santa Chiara Regional Hospital, APSS, Trento, Italy.
² Department of Surgical Sciences and Integrated Diagnostics, University of Genoa, Genoa, Italy.
³ Anesthesia and Intensive Care, IRCCS Ospedale Policlinico San Martino, Genoa, Italy.
⁴ Centre for Medical Sciences - CISMed, University of Trento, Trento, Italy.

PMID: 39511753
DOI: 10.4103/mgr.MEDGASRES-D-24-00051

Abstract

Recently, advancements in extracorporeal carbon dioxide removal (ECCO2R) technology have markedly enhanced its clinical applicability and efficacy for managing severe respiratory conditions. This review highlights critical innovations in ECCO2R, such as advanced catheter technologies, active mixing methods, and biochemical enhancements, which have substantially improved gas exchange efficiency and broadened the scope of ECCO2R applications. Integrating ECCO2R into acute and chronic respiratory care has led to a shift toward more mobile and less invasive modalities, promising for extending ECCO2R usage from intensive care units to home settings. By examining these technological advancements and their clinical impacts, this paper outlines the potential future directions of ECCO2R technology, emphasizing its role in transforming respiratory care practices and enhancing patient outcomes.