Ocular scedosporiosis: A case series

Marcus L Turner; Minh Nguyen; Julie Schallhorn; Gerami D Seitzman

doi:10.1016/j.ajoc.2024.102190

Ocular scedosporiosis: A case series

Am J Ophthalmol Case Rep. 2024 Oct 16:36:102190. doi: 10.1016/j.ajoc.2024.102190. eCollection 2024 Dec.

Authors

Marcus L Turner^{1

2

3}, Minh Nguyen^{1

2

3}, Julie Schallhorn², Gerami D Seitzman^{2

3}

Affiliations

¹ Department of Ophthalmology, University of Washington, Seattle, WA, USA.
² Department of Ophthalmology, University of California San Francisco, San Francisco, CA, USA.
³ Proctor Foundation, University of California San Francisco, San Francisco, CA, USA.

Abstract

Purpose: To report five cases of ocular scedosporiosis with associated predisposing factors, treatment courses, and clinical outcomes.

Observation: This case series consists of 5 patients diagnosed with ocular scedosporiosis. Two patients were female and 3 were male. The average age was 68.4 years (range 53-85). Four of the 5 had a clear history of ocular surgery or ocular trauma with organic foreign material. Two developed sclero-keratitis. Two had cornea-only involvement. There was 1 scleritis-only case. Patients with scleritis required topical and systemic treatment. Patients with only keratitis were treated topically. The two patients with sclero-keratitis ultimately progressed to eye removal despite maximal therapy.

Conclusion and importance: Ocular scedosporiosis is exceedingly rare, especially in the Unites States. We highlight similarities and differences of five ocular scedosporiosis cases. Most cases involved either ocular surgery or contamination with ground or plant matter. This case series highlights the challenge of the diagnosis and the aggressivity of this disease.

Keywords: Infectious keratitis; Infectious scleritis; Scedosporium.

Publication types

Case Reports