Diagnosis and management of shrimp allergy

Front Allergy. 2024 Oct 18:5:1456999. doi: 10.3389/falgy.2024.1456999. eCollection 2024.

Abstract

Shrimp allergy, the most common food allergy in the United States, affects up to 2% of the population. Its etiology is multi-factorial with the combination of genetic predisposition and environmental exposures. This review summarizes the latest diagnosis and management strategies for shrimp allergy. Currently, the double-blind, placebo-controlled food challenge is the gold standard for diagnosis. Moreover, mainstream and experimental management strategies include food allergen avoidance, the FDA-approved omalizumab, and oral immunotherapy. Herein, we emphasize the urgent need to develop more effective diagnostic tools and therapies for shrimp allergy.

Keywords: diagnosis; environmental exposure; genetics; management; shrimp allergy; specific IgE.

Publication types

  • Review

Grants and funding

The author(s) declare that financial support was received for the research, authorship, and/or publication of this article. CD’s NIH-NIAID Grant #1R34AI57948–01.