Burden of diabetes mellitus in Weifang: Changing trends in prevalence and deaths from 2010 to 2021

PLoS One. 2024 Oct 30;19(10):e0312871. doi: 10.1371/journal.pone.0312871. eCollection 2024.

Abstract

Objective: The objective of this study is to analyze the death characteristics and burden of disease (BOD) in diabetes mellitus (DM) patients in Weifang from 2010 to 2021. The findings will serve as a foundational data source and theoretical framework for public health administrative departments in the formulation of DM-related policies.

Methods: The annual percent change (APC) and average annual percent change (AAPC) of the disability-adjusted life years (DALY), years of life lost (YLL), and years lived with disability (YLD) in DM residents from 2010 to 2021 were analyzed using the Joinpoint software to reflect the changing trend of the BOD in DM patients. Additionally, we conducted an analysis of the various causes of death among these patients and compared BOD in diabetic patients with different backgrounds.

Results: From 2010 to 2021, the burden of disease, which includes DALY, YL, and YLD, has been increasing among patients with DM in Weifang. It is noteworthy that the burden of disease is particularly pronounced among male patients and those aged 75 or above. Additionally, it is observed that widowed and illiterate DM patients have comparatively longer survival times. Furthermore, among the DM patients who have unfortunately passed away, it has been identified that unspecified DM with ketoacidosis accounts for 10.03% of the deaths as a direct cause of death. In contrast, type 2 diabetes mellitus (T2DM) with kidney complications contributes to 10.23% of the deaths as the fundamental cause of death.

Conclusion: The city is faced with a significant challenge of diabetes, which is influenced by factors such as gender, age, cultural background, and marital status. Unspecified diabetes mellitus (DM) with ketoacidosis (10.03%) and T2DM with renal complications (0.23%) are identified as the primary direct and underlying causes of death among diabetic patients, respectively. This study serves as a valuable reference for other regions in terms of diabetes prevention, control, and the management of chronic diseases.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Cause of Death
  • Child
  • China / epidemiology
  • Cost of Illness
  • Diabetes Mellitus* / epidemiology
  • Diabetes Mellitus* / mortality
  • Disability-Adjusted Life Years
  • Female
  • Humans
  • Male
  • Middle Aged
  • Prevalence
  • Young Adult

Grants and funding

This work was supported by the Project of Weifang Municipal Health Commission (WFWSJK-2022-272). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.