40 years since the Heidelberg genetic screen that revolutionized developmental and cell biology

Abstract

Our current understanding of the molecular basis of embryonic development and the shared machinery underlying this remarkable process has its roots in three papers published 40 years ago, which summarize the results of the Nobel Prize-winning 'Heidelberg screen'. The genesis of these experiments that empowered us and the stories behind the experiments are worth revisiting.

Keywords: Embryonic development; Heidelberg screen.