Salvage Surgery for Unifocal Progressive Metastatic Mismatch Repair-Deficient GI Cancer Responding to Immune Checkpoint Inhibition

JCO Precis Oncol. 2024 Oct:8:e2400176. doi: 10.1200/PO.24.00176. Epub 2024 Oct 11.

Abstract

Case series describing excellent outcomes for patients with dMMR GI cancer after resection of a single progressive lesion under immunotherapy.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • DNA Mismatch Repair*
  • Female
  • Gastrointestinal Neoplasms / drug therapy
  • Gastrointestinal Neoplasms / pathology
  • Gastrointestinal Neoplasms / surgery
  • Humans
  • Immune Checkpoint Inhibitors* / therapeutic use
  • Male
  • Middle Aged
  • Salvage Therapy*

Substances

  • Immune Checkpoint Inhibitors