Complete genome sequences of three Pseudomonas aeruginosa jumbo bacteriophages discovered in Kenya

Lillian Musila; Jordan T Bird; Katie R Margulieux; Collins Kigen; Nino Mzhavia; Andrey A Filippov; Mikeljon P Nikolich

doi:10.1128/mra.00684-24

Complete genome sequences of three Pseudomonas aeruginosa jumbo bacteriophages discovered in Kenya

Microbiol Resour Announc. 2024 Nov 12;13(11):e0068424. doi: 10.1128/mra.00684-24. Epub 2024 Oct 8.

Authors

Lillian Musila^#¹, Jordan T Bird^#², Katie R Margulieux³, Collins Kigen¹, Nino Mzhavia³, Andrey A Filippov³, Mikeljon P Nikolich³

Affiliations

¹ Department of Emerging Infectious Diseases, Walter Reed Army Institute of Research-Africa, Kericho, Kenya.
² Department of Biochemistry and Molecular Biology, University of Arkansas, Little Rock, Arkansas, USA.
³ Wound Infections Department, Bacterial Diseases Branch, Walter Reed Army Institute of Research, Silver Spring, Maryland, USA.

^# Contributed equally.

Abstract

The genomes of three Pseudomonas aeruginosa Phikzvirus bacteriophages isolated in Kenya are described. The genomes of phages vB_PaePAO1-KEN19, vB_Pae3705-KEN49, and vB_Pae10145-KEN51, respectively, had lengths of 278,921, 280,231, and 280,173 bp, with 36.93%, 36.84%, and 36.86% GC content, containing 419, 417, and 417 coding sequences (including seven tRNAs in each genome).

Keywords: Kenya; Phikzvirus; Pseudomonas aeruginosa; bacteriophage; bacteriophage therapy; genome.

Grants and funding

PR182667/DOD | USA | MEDCOM | Congressionally Directed Medical Research Programs (CDMRP)