Pulmonary endoscopy - central to an interventional pulmonology program

Expert Rev Respir Med. 2024 Nov;18(11):843-860. doi: 10.1080/17476348.2024.2413561. Epub 2024 Oct 28.

Abstract

Introduction: Pulmonary endoscopy occupies a central role in Interventional Pulmonology and is frequently the mainstay of diagnosis of respiratory disease, in particular lung malignancy. Older techniques such as rigid bronchoscopy maintain an important role in central airway obstruction. Renewed interest in the peripheral pulmonary nodule is driving major advances in technologies to increase the diagnostic accuracy and advance new potential endoscopic therapeutic options.

Areas covered: This paper describes the role of pulmonary endoscopy, in particular ultrasound in the diagnosis and staging of lung malignancy. We will explore the recent expansion of ultrasound to include endoscopic ultrasound - bronchoscopy (EUS-B) and combined ultrasound (CUS) techniques. We will discuss in detail the advances in the workup of the peripheral pulmonary nodule.We performed a non-systematic, narrative review of the literature to summarize the evidence regarding the indications, diagnostic yield, and safety of current bronchoscopic sampling techniques.

Expert opinion: EBUS/EUS-B has revolutionized the diagnosis and staging of thoracic malignancy resulting in more accurate assessment of the mediastinum compared to mediastinoscopy alone, thus reducing the rate of futile thoracotomies. Although major advances in the assessment of the peripheral pulmonary nodule have been made, the role of endoscopy in this area requires further clarification and investigation.

Keywords: Interventional pulmonology; bronchoscopy; combined ultrasound (CUS); endobronchial ultrasound (EBUS); endobronchial valves; endoscopic ultrasound-bronchoscopy (EUS-B); navigation bronchoscopy; peripheral pulmonary lesion.

Publication types

  • Review

MeSH terms

  • Bronchoscopy* / instrumentation
  • Endosonography*
  • Humans
  • Lung Neoplasms* / diagnosis
  • Lung Neoplasms* / diagnostic imaging
  • Lung Neoplasms* / pathology
  • Neoplasm Staging
  • Predictive Value of Tests
  • Pulmonary Medicine