Objectives: To summarize the best evidence for the management of ovarian hyperstimulation syndrome in patients undergoing assisted reproductive therapy.
Methods: Evidence related to the management of ovarian hyperstimulation syndrome in patients undergoing assisted reproductive therapy, including practice guidelines, systematic evaluation, expert consensuws and evidence summary was systematically searched in UpToDate, BMJ Best Practice, World Health Organization (WHO) website, Guidelines International Network (GIN), National Institute for Health and Clinical Excellence (NICE) website, National Guidelines website, American Society for Reproductive Medicine (ASRM) website, New York Academy of Sciences (NYAS) website, Joanna Briggs Institute (JBI) database, Cochrane Library, CINAHL, PubMed, Wanfang Knowledge Data Service Platform, CNKI, and China Biomedical Literature Database from inception to March 1, 2024. Two researchers independently evaluated the quality of the literature, and a senior researcher made the final decision for literature inclusion.
Results: A total of 14 articles met the criteria, including 5 practical guidelines, 3 systematic evaluations, 2 expert consensuses, 1 evidence summary paper and 3 from UptoDate. The final formation includes five aspects: risk assessment, disease monitoring, early prevention, institutional management, and health education, with a total of 27 best pieces of evidence.
Conclusions: The updated evidence indicates that the monitoring and prevention of ovarian hyperstimulation syndrome should start early; medical practitioners should provide personalized treatment plans for patients, promote the rational allocation of treatment resources, and enhance effective management of ovarian hyperstimulation syndrome.
目的: 总结辅助生殖技术治疗患者卵巢过度刺激综合征管理的最佳证据，为医护人员管理卵巢过度刺激综合征提供循证依据。方法: 系统检索UpToDate、BMJ Best Practice、世界卫生组织（WHO）网站、国际指南协作网（GIN）、英国国家医疗保健优化研究所（NICE）网站、美国国立指南网、美国生殖医学会（ASRM）网站、纽约科学院（NYAS）网站、澳大利亚乔安娜布里格斯研究所（JBI）循证卫生保健中心数据库、Cochrane Library、CINAHL、PubMed、万方数据知识服务平台、中国知网和中国生物医学文献数据库中与辅助生殖技术治疗患者卵巢过度刺激综合征管理有关的证据，包括实践指南、系统评价、专家共识、证据总结。检索时限为建库至2024年3月1日。两名受过循证护理培训的研究人员对文献独立进行质量评价，出现分歧时交第三名循证护理专家进行判断，最终决定纳入或剔除文献。结果: 共纳入14篇文献，包括5篇实践指南、3篇系统评价、2篇专家共识、1篇证据总结和UptoDate中的3篇。最终得到包括风险评估、病情监测、早期预防、制度管理、健康教育五个方面共27条最佳证据。结论: 医护人员应早期开展卵巢过度刺激综合征的监测和预防，为患者提供个性化的治疗方案，促使治疗资源得到合理配置，以提升对卵巢过度刺激综合征患者的有效管理。.
Keywords: Assisted reproductive technology; Evidence summary; Management; Ovarian hyperstimulation syndrome.