The Association Between Screening for Colorectal Cancer and Mental and Physical Health

Cancer Control. 2024 Jan-Dec:31:10732748241285492. doi: 10.1177/10732748241285492.

Abstract

Background: Colorectal cancer screening reduces colorectal cancer morbidity and mortality. Identifying the factors associated with screening participation is needed to overcome barriers to screening. While several of those factors have been identified, the impact of mental and physical health on screening behaviour is not well understood.

Methods: This retrospective cohort study compared the self-reported mental and physical health of those who did screen for colorectal cancer and those who did not. Participants of the Australasian Colorectal Cancer Family Registry Cohort that were aged 45-75 years and had never been diagnosed with colorectal cancer were asked to complete a questionnaire detailing their colorectal cancer screening participation in the preceding 5 years, and a validated questionnaire of mental and physical health. Multivariable logistic regression was used to adjust for measured potential confounders.

Results: Of the 1130 eligible participants, 781 had a family history of colorectal cancer (69.5%), and 819 reported colorectal cancer screening in the past 5 years (72%). After adjusting for potential confounders, there was no evidence that overall mental or physical health was associated with colorectal cancer screening. However, those reporting higher levels of general health were more likely to participate in colorectal cancer screening (OR = 1.02 (100 point scale), 95% CI 1.004, 1.037, P = .014).

Conclusion: We found limited evidence that mental and physical health were associated with colorectal cancer screening. The high proportion of participants with a family history of colorectal cancer limits the generaliseability of the findings to the general population, although we observed no differences in findings by strength of family history.

Keywords: Australian national bowel cancer screening program; cancer screening; colorectal cancer; epidemiology; mental health; physical health; short form 12.

MeSH terms

  • Aged
  • Colorectal Neoplasms* / diagnosis
  • Colorectal Neoplasms* / epidemiology
  • Early Detection of Cancer* / methods
  • Early Detection of Cancer* / psychology
  • Early Detection of Cancer* / statistics & numerical data
  • Female
  • Health Status
  • Humans
  • Male
  • Mass Screening / methods
  • Mass Screening / statistics & numerical data
  • Mental Health* / statistics & numerical data
  • Middle Aged
  • Retrospective Studies
  • Surveys and Questionnaires