Recent advances in pathogenesis, diagnosis, and therapeutic approaches for digestive system involvement in systemic lupus erythematosus

J Dig Dis. 2024 Jul;25(7):410-423. doi: 10.1111/1751-2980.13307. Epub 2024 Sep 24.

Abstract

Systemic lupus erythematosus (SLE) is a systemic autoimmune disease characterized by the presence of large amounts of autoantibodies and immune complex formation. Because of their atypical clinical symptoms, SLE patients with digestive system involvement may not be recognized or treated precisely and extensively. Clinicians should pay close attention to SLE with digestive system involvement, as these conditions can easily worsen the condition and possibly endanger the patient's life. In this review we summarized the pathogenesis, pathological characteristics, clinical manifestations, diagnosis, and therapies for digestive system involvement in SLE.

Keywords: diagnosis; digestive system involvement; etiology; systemic lupus erythematosus; therapy.

Publication types

  • Review

MeSH terms

  • Digestive System Diseases* / diagnosis
  • Digestive System Diseases* / etiology
  • Digestive System Diseases* / therapy
  • Humans
  • Lupus Erythematosus, Systemic* / complications
  • Lupus Erythematosus, Systemic* / diagnosis
  • Lupus Erythematosus, Systemic* / therapy