Precise prediction of size of a foldable capsular vitreous body via computerized three-dimensional ocular reconstruction in severe retinal detachment

Chongde Long; Qianying Gao; Shenwen Liu; Yan Chen; Huping Song; Jinguo Yu; Bingsheng Lou; Zhaohui Yuan; Yongxin Zheng; Liuxueying Zhong; Siqi Qiao; Xiangda Meng; Yuanyuan Liu; Yingyu Wang; Yuanyuan Liu; Xiaofeng Lin; Hua Yan

doi:10.1186/s12886-024-03646-9

Precise prediction of size of a foldable capsular vitreous body via computerized three-dimensional ocular reconstruction in severe retinal detachment

BMC Ophthalmol. 2024 Sep 20;24(1):412. doi: 10.1186/s12886-024-03646-9.

Authors

Chongde Long^#¹, Qianying Gao^#², Shenwen Liu³, Yan Chen⁴, Huping Song⁵, Jinguo Yu⁶, Bingsheng Lou¹, Zhaohui Yuan¹, Yongxin Zheng¹, Liuxueying Zhong¹, Siqi Qiao², Xiangda Meng⁶, Yuanyuan Liu⁶, Yingyu Wang², Yuanyuan Liu², Xiaofeng Lin⁷, Hua Yan^{8

9

10

11}

Affiliations

¹ State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Sun Yat-sen University, Guangzhou, 510060, China.
² Vesber Vitreous Institute, Guangzhou, 510060, China.
³ Shenzhen Eye Hospital, Shenzhen, China.
⁴ Xiamen Eye Center of Xiamen University, Xiamen, China.
⁵ Xi'an People's Hospital (Xi'an Fourth Hospital), Xian, China.
⁶ Tianjin Medical University General Hospital, Tianjin, China.
⁷ Aier Ophthalmology Institute, Aier Mansion, No.188 South Furong Road, Changsha City, Hunan province, China. linxiaof@mail.sysu.edu.cn.
⁸ Tianjin Medical University General Hospital, Tianjin, China. zyyyanhua@tmu.edu.cn.
⁹ Laboratory of Molecular Ophthalmology, School of Basic Medical Sciences, Tianjin Medical University, Tianjin, China. zyyyanhua@tmu.edu.cn.
¹⁰ Medical School of Nankai University, Tianjin, China. zyyyanhua@tmu.edu.cn.
¹¹ Department of Ophthalmology, Tianjin Medical University General Hospital Medical School of Nankai University, Tianjin, 300052, China. zyyyanhua@tmu.edu.cn.

^# Contributed equally.

PMID: 39304858
DOI: 10.1186/s12886-024-03646-9

Abstract

Background: This study aimed to precisely predict the size and silicone oil injection of a foldable capsular vitreous body (FCVB) via computerized three-dimensional (3D) ocular reconstruction in the treatment of severe retinal detachment in China.

Methods: The 3D software Unigraphics NX was applied to determine the volume of the inner cavity with 16-30 mm axial length, assigning the anterior and posterior chambers, the FCVB sizes, and the silicone oil injection volume, and modeling the data between the axial length and the FCVB size. In clinical practice, IOL Master was applied to accurately measure the axial length of the contralateral healthy eye to anchor the anterior-posterior and horizontal diameters of the operated eye in horizontal position CT, and compared with the model to recommend the FCVB size and silicone oil amount, and the clinical effect was validated in cases across five hospitals in China.

Results: For the axial length of 16-30 mm, the volume of the inner cavity is 1.2 ml-8.4 ml. FCVB size and silicone oil volume were recommended based on this volume of the inner cavity. Of 253 cases, we noted 11 cases implanted with AV-10P and 1.05 ± 0.21 ml of silicone oil, 41 with AV-12P and 1.58 ± 0.18 ml of silicone oil, 163 with AV-13.5P and 2.48 ± 0.29 ml of silicone oil, 31 with AV-15P and 3.57 ± 0.39 ml of silicone oil, and 7 with AV-17P and 5.71 ± 0.81 ml of silicone oil. There was no significant difference in postoperative visual acuity scores compared with preoperative (P = 0.097), postoperative IOP(10.29 ± 0.57mmHg)was slightly higher than preoperative IOP (9.76 ± 0.48 mmHg), but there was still no statistically significant difference between the two comparisons (P = 0.405).

Conclusion: Three-dimensional reconstruction prediction is a good solution for eyeballs with obvious individualized changes in severe retinal detachment, and this method helps doctors standardize FCVB size selection and the silicone oil amount for patients.

Keywords: 3D reconstruction; FCVB; Retinal detachment; Silicone oil.