Pembrolizumab in HER2-Positive Gastric Cancer

N Engl J Med. 2024 Oct 10;391(14):1360-1362. doi: 10.1056/NEJMc2408121. Epub 2024 Sep 14.
No abstract available

Publication types

  • Clinical Trial, Phase III
  • Letter
  • Multicenter Study
  • Randomized Controlled Trial

MeSH terms

  • Adenocarcinoma* / drug therapy
  • Adenocarcinoma* / mortality
  • Adenocarcinoma* / pathology
  • Aged
  • Antibodies, Monoclonal, Humanized* / therapeutic use
  • Antineoplastic Agents, Immunological* / adverse effects
  • Antineoplastic Agents, Immunological* / therapeutic use
  • Antineoplastic Combined Chemotherapy Protocols
  • Double-Blind Method
  • Esophagogastric Junction / pathology
  • Female
  • Humans
  • Male
  • Middle Aged
  • Progression-Free Survival
  • Receptor, ErbB-2* / analysis
  • Receptor, ErbB-2* / metabolism
  • Stomach Neoplasms* / drug therapy
  • Stomach Neoplasms* / mortality
  • Stomach Neoplasms* / pathology
  • Trastuzumab / therapeutic use

Substances

  • Antibodies, Monoclonal, Humanized
  • Antineoplastic Agents, Immunological
  • ERBB2 protein, human
  • pembrolizumab
  • Receptor, ErbB-2
  • Trastuzumab