Successful Treatment of Cryptococcus gattii in an Immunocompetent Adult Rhesus Macaque (Macaca mulatta)

J Med Primatol. 2024 Oct;53(5):e12733. doi: 10.1111/jmp.12733.

Abstract

An adult female rhesus macaque presented during routine annual physical examination for evaluation of a 2.5-cm diameter superficial ulcerated dermal lesion that was subsequently diagnosed as a systemic fungal infection caused by Cryptococcus gattii. Cryptococcus gattii is one of several basidiomycetic yeasts responsible for pulmonary, neurologic, and disseminated infections in humans and animals. This report describes the diagnosis, management, and clinical resolution of a C. gattii infection in an immunocompetent 5-year-old female rhesus macaque.

Keywords: Cryptococcus; Cryptococcus gattii; Macaca mulatta; cryptococcosis; disseminated fungal; fungal infection; macaca.

Publication types

  • Case Reports

MeSH terms

  • Animals
  • Antifungal Agents* / therapeutic use
  • Cryptococcosis* / diagnosis
  • Cryptococcosis* / drug therapy
  • Cryptococcosis* / microbiology
  • Cryptococcosis* / veterinary
  • Cryptococcus gattii* / isolation & purification
  • Female
  • Immunocompetence
  • Macaca mulatta*
  • Monkey Diseases* / diagnosis
  • Monkey Diseases* / drug therapy
  • Monkey Diseases* / microbiology

Substances

  • Antifungal Agents