Hodgkin/Reed-Sternberg cells induce GPNMB expression and release from macrophages to suppress T-cell responses to the Epstein-Barr virus-encoded LMP2A protein
Haematologica. 2024 Aug 22.
doi: 10.3324/haematol.2024.285319.
Online ahead of print.
1 Institute of Cancer and Genomic Sciences, University of Birmingham, Birmingham.
2 Institute of Cancer and Genomic Sciences, University of Birmingham.
3 Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham.
4 Limerick Digital Cancer Research Centre, Bernal Institute and Health Research Institute and School of Medicine, University of Limerick, Limerick.
5 Institute of Cancer and Genomic Sciences, University of Birmingham, Birmingham, United Kingdom; The Palatine Centre, Durham University, Durham.
6 Department of Pediatrics, Faculty of Medicine and Dentistry, Palacky University and University Hospital Olomouc, Olomouc, Czech Republic.
7 University Hospitals Plymouth NHS Trust, Plymouth.
8 Institute of Cancer and Genomic Sciences, University of Birmingham, Birmingham, United Kingdom; National Institute for Health Research (NIHR) Birmingham Biomedical Research Centre University of Birmingham, Birmingham.
9 Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham, United Kingdom; Royal College of Surgeons in Ireland Medical University of Bahrain, Manama, PO Box 15503, Bahrain. k.vrzalikova@bham.ac.uk.
10 Limerick Digital Cancer Research Centre, Bernal Institute and Health Research Institute and School of Medicine, University of Limerick, Limerick, Ireland; Royal College of Surgeons in Ireland Medical University of Bahrain, Manama, Bahrain; Department of Clinical and Molecular Pathology, Institute of Molecular and Translational Medicine, Faculty of Medicine and Dentistry, Palacky University and University Hospital Olomouc, Olomouc. paul.murray@ul.ie.