Magseed application for detecting recurrent lymph node metastasis in papillary thyroid cancer: A novel minimally invasive Approach

Ivan Shabo; Athanasios Zouzos; Hanna Fredholm; Robert Bränström; Anders Höög; Magnus Kjellman; Catharina Ihre-Lundgren

doi:10.1016/j.ejso.2024.108624

Magseed application for detecting recurrent lymph node metastasis in papillary thyroid cancer: A novel minimally invasive Approach

Eur J Surg Oncol. 2024 Aug 28;50(11):108624. doi: 10.1016/j.ejso.2024.108624. Online ahead of print.

Authors

Ivan Shabo¹, Athanasios Zouzos², Hanna Fredholm³, Robert Bränström³, Anders Höög⁴, Magnus Kjellman³, Catharina Ihre-Lundgren³

Affiliations

¹ Department of Breast, Endocrine Tumors, and Sarcoma, Karolinska University Hospital, SE 171 76, Stockholm, Sweden; Department of Molecular Medicine and Surgery, Karolinska Institutet, SE 171 77, Stockholm, Sweden. Electronic address: ivan.shabo@ki.se.
² Department of Oncology-Pathology, Karolinska Institutet, SE 171 77, Stockholm, Sweden; Department of Radiology, Karolinska University Hospital, SE 171 76, Stockholm, Sweden.
³ Department of Breast, Endocrine Tumors, and Sarcoma, Karolinska University Hospital, SE 171 76, Stockholm, Sweden; Department of Molecular Medicine and Surgery, Karolinska Institutet, SE 171 77, Stockholm, Sweden.
⁴ Department of Oncology-Pathology, Karolinska Institutet, SE 171 77, Stockholm, Sweden; Department of Pathology, Karolinska University Hospital, SE 171 76, Stockholm, Sweden.

PMID: 39208690
DOI: 10.1016/j.ejso.2024.108624

Abstract

Papillary thyroid cancer is associated with lymph node metastasis and tumor recurrence that need repeated surgery, entailing surgical challenges with a high risk of complications such as nerve damage and bleeding. Magseed is a metal coil used to detect non-palpable lesions and is an established modality in breast cancer surgery. In this case series, we explore the feasibility of Magseed in metastasis surgery of papillary thyroid cancer. Under the guidance of ultrasonography, Magseed is injected into the target tissue and intraoperatively detected with a handheld magnetometer probe, Sentimag®. Five patients with recurrence of papillary thyroid cancer were operated on with focused Magseed-guided localization. All patients had repeated surgery and radioiodine treatments. Four of the patients had lymph node metastasis hidden in the fibrosis, and one patient had recurrent tumor tissue on the left side of the larynx. Magseed was easy to use, safe, and precise in detecting the target tissue.

Keywords: Magseed; Metastasis; Minimally invasive surgery; Papillary thyroid cancer.