Systems Biology Approach Uncovers Candidates for Liver-Heart Interorgan Crosstalk in HFpEF

Affiliations

• ¹ Deutsches Herzzentrum der Charité (S.S., L.L., R.W., S.P.H., F.C., D.B., T.E., L.S.P., M.M., C.U.O., S.A.D., S.V.L.C., G.G.S.), Charité-Universitätsmedizin Berlin, Germany.
• ² German Centre for Cardiovascular Research (DZHK), Partner Site Berlin, Germany (S.S., L.L., R.W., S.P.H., F.C., D.B., N.N., T.E., L.S.P., M.M., C.U.O., U.K., G.G.S.).
• ³ Translational Approaches in Heart Failure and Cardiometabolic Disease, Max Delbrück Center for Molecular Medicine in the Helmholtz Association, Berlin, Germany (F.C., N.N., L.S.P., C.F., A.V., S.J., G.G.S.).
• ⁴ Division of Internal Medicine, Department of Medicine, University of Padua, Italy (F.C.).
• ⁵ Department of Medicine, Clinica Medica, University of Udine, Italy (A.V.).
• ⁶ Institute of Pharmacology, Max Rubner Center for Cardiovascular Metabolic Renal Research (U.K.), Charité-Universitätsmedizin Berlin, Germany.
• ⁷ Department of Biological Chemistry, Center for Epigenetics and Metabolism, University of California, Irvine (M.Z., M.S.).
• ⁸ Division of Cardiology, Department of Advanced Biomedical Sciences, Federico II University, Naples, Italy (G.G.S.).