We identified 3 clades of dengue virus serotype 3 belonging to genotype III isolated during 2019-2020 in Jamaica by using whole-genome sequencing and phylogenomic and phylogeographic analyses. The viruses likely originated from Asia in 2014. Newly expanded molecular surveillance efforts in Jamaica will guide appropriate public health responses.
Keywords: Caribbean; Jamaica; dengue; dengue virus; dengue virus serotype 3; genotype; sequence; serotype; vector-borne infections; viruses; zoonoses.