Coexistence of low body mass index and poor oral health negatively affects activities of daily living, swallowing, and cognition after stroke

Geriatr Gerontol Int. 2024 Oct;24(10):1045-1052. doi: 10.1111/ggi.14971. Epub 2024 Aug 27.

Abstract

Aim: Low body mass index (BMI) and poor oral health are prevalent among older stroke patients and associated with adverse outcomes. However, their combined impact on functional recovery after stroke remains unclear. This study investigated the synergistic effects of low BMI and poor oral health on activities of daily living (ADL) independence, swallowing function, and cognitive status in post-stroke older patients.

Methods: A retrospective cohort study was conducted on 708 hospitalized post-stroke patients aged ≥70 years. Low BMI was defined as <20 kg/m2, and poor oral health was assessed using the Revised Oral Assessment Guide (ROAG) with a score ≥13 indicating oral problems. The primary outcome was ADL independence (Functional Independence Measure-motor score >78) at discharge. Secondary outcomes included swallowing level (Food Intake Level Scale) and cognitive status (Functional Independence Measure-cognition score). Multiple regression analyses were performed to examine the associations of low BMI, poor oral health, and their combination with outcomes of interest.

Results: The coexistence of low BMI and poor oral health was independently associated with lower odds of achieving ADL independence (odds ratio 0.130, 95% confidence interval [CI] 0.023-0.718), worse swallowing level (B = -0.878, 95% CI -1.280 to -0.476), and poorer cognitive status (B = -1.872, 95% CI -2.960 to -0.784) at discharge, after adjusting for confounders. The combined impact was stronger than either condition alone.

Conclusions: The coexistence of low BMI and poor oral health exerts a synergistic negative impact on functional recovery in older stroke inpatients. Comprehensive interventions integrating nutritional support, oral management, and rehabilitation are crucial to optimizing outcomes in this vulnerable population. Geriatr Gerontol Int 2024; 24: 1045-1052.

Keywords: convalescent rehabilitation; dysphagia; malnutrition; oral problems; sarcopenia.

MeSH terms

  • Activities of Daily Living*
  • Aged
  • Aged, 80 and over
  • Body Mass Index*
  • Cognition* / physiology
  • Cohort Studies
  • Deglutition / physiology
  • Deglutition Disorders / etiology
  • Deglutition Disorders / physiopathology
  • Female
  • Geriatric Assessment / methods
  • Humans
  • Male
  • Oral Health*
  • Recovery of Function
  • Retrospective Studies
  • Stroke Rehabilitation* / methods
  • Stroke* / complications
  • Stroke* / physiopathology