Tumour masquerading juvenile angiofibroma in a female; unveiling glomangiopericytoma-a rare sinonasal histopathology

BMJ Case Rep. 2024 Aug 24;17(8):e256667. doi: 10.1136/bcr-2023-256667.

Abstract

Sinonasal tumours of varying histology are not unusual in otolaryngology surgical practice. Juvenile angiofibroma (JAs) are vascular tumours usually occurring in adolescent male population; but rare in females. But similar clinical and radiological presentations are possible in females inducing strong suspicion of JA which needs to be ruled out by detailed evaluation. Here we present a case of a young female in her 20s who presented with a bleeding nasal mass which was finally diagnosed as sinonasal glomangiopericytoma which is a very rare sinonasal tumour. Tumours resembling JA do present in the female population but rarely turn out to be JA. A strong index of suspicion along with a handful of special blood investigations to rule out androgen insensitivity syndrome is mandatory.

Keywords: Ear, nose and throat; Head and neck cancer; Interventional radiology; Otolaryngology / ENT.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Angiofibroma* / diagnosis
  • Angiofibroma* / pathology
  • Diagnosis, Differential
  • Female
  • Hemangiopericytoma* / diagnosis
  • Hemangiopericytoma* / diagnostic imaging
  • Hemangiopericytoma* / pathology
  • Humans
  • Paranasal Sinus Neoplasms / diagnosis
  • Paranasal Sinus Neoplasms / diagnostic imaging
  • Paranasal Sinus Neoplasms / pathology