Factors Associated With Non-Uptake of Implantable Cardioverter-Defibrillator (ICD) Among Eligible Patients at a Tertiary Hospital in Kenya

Glob Heart. 2024 Aug 16;19(1):66. doi: 10.5334/gh.1346. eCollection 2024.

Abstract

Background: Efficacy of Implantable Cardioverter-Defibrillator (ICD) implantation in both primary and secondary prevention of Sudden Cardiac Death (SCD) in at-risk population is well established. ICD implantation rates remain low particularly in Africa with a paucity of data regarding factors associated with non-uptake.

Objectives: The primary study objective was to determine the factors associated with non-uptake of ICD among heart failure (HF) patients with reduced ejection fraction (EF<35%). Reasons for ICD refusal among eligible patients were reviewed as a secondary objective.

Methods: This was a retrospective study among HF patients eligible for ICD implantation evaluated between 2018 to 2020. Comparison between ICD recipient and non-recipient categories was made to establish determinants of non-uptake.

Results: Of 206 eligible patients, only 69 (33.5%) had an ICD. Factors independently associated with non-uptake were lack of private insurance (42.3% vs 63.8%; p = 0.005), non-cardiology physician (16.1% vs 5.8%; p = 0.045) and non-ischemic cardiomyopathy (54.7% vs 36.4% p = 0.014). The most common (75%) reason for ICD refusal was inability to pay for the device.

Conclusion: ICDs are underutilized among eligible HF with reduced EF patients in Kenya. The majority of patients without ICD had no private insurance, had non-ischemic cardiomyopathy and non-cardiology primary physician. Early referral of HF with reduced EF patients to HF specialists to optimize guideline-directed medical therapy and make ICD recommendation is needed.

Keywords: Implantable Cardioverter-Defibrillator (ICD); Sub-Saharan Africa (SSA); non-uptake.

MeSH terms

  • Adult
  • Aged
  • Death, Sudden, Cardiac* / epidemiology
  • Death, Sudden, Cardiac* / prevention & control
  • Defibrillators, Implantable* / statistics & numerical data
  • Female
  • Heart Failure* / epidemiology
  • Heart Failure* / therapy
  • Humans
  • Kenya / epidemiology
  • Male
  • Middle Aged
  • Primary Prevention / methods
  • Retrospective Studies
  • Stroke Volume / physiology
  • Tertiary Care Centers*