Microwave Synthesis of Fluorescent Carbon Quantum dots from Araucaria Heterophylla Gum: Application in Drug Detection

Rohitash Kumar; Vimal K Bhardwaj

doi:10.1007/s10895-024-03874-8

Microwave Synthesis of Fluorescent Carbon Quantum dots from Araucaria Heterophylla Gum: Application in Drug Detection

J Fluoresc. 2024 Aug 10. doi: 10.1007/s10895-024-03874-8. Online ahead of print.

Authors

Rohitash Kumar¹, Vimal K Bhardwaj²

Affiliations

¹ Department of Chemistry, Dr. B. R. Ambedkar National Institute of Technology, Jalandhar, Punjab, India.
² Department of Chemistry, Dr. B. R. Ambedkar National Institute of Technology, Jalandhar, Punjab, India. bhardwajvk@nitj.ac.in.

PMID: 39126608
DOI: 10.1007/s10895-024-03874-8

Abstract

This study employed a green microwave synthesis technique to produce carbon quantum dots (CQDs) from araucaria heterophylla gum extract. The produced CQDs emit a distinct blue fluorescent light, contributing a remarkable quantum yield of 14.69%. Their average particle size measures at 1.62 ± 0.39 nm. Furthermore, these CQDs demonstrate excellent water solubility and maintain high fluorescence stability despite ionic strength, pH and time variations. Moreover, we present here for the first time that the synthesized CQDs demonstrate a rapid, exceptionally sensitive, and discerning fluorescence quenching phenomenon (IFE) concerning Cefprozil (CPR). The fluorescent probe was sensitive and specific with good linear relationships for CPR in the 0-18 µM range. The limit of detection for relationships for CPR was 2.51 µM. This study provides novel opportunities for producing high-quality luminescent CQDs that meet the requirements for various biological and environmental applications.

Keywords: Araucaria heterophylla gum; Carbon quantum dots (CQDs); Cefprozil (CPR); Fluorescence quenching effect (IFE); Fluorescent probe.