Periorbital necrotizing fasciitis: clinical perspectives on nine cases

Eur J Clin Microbiol Infect Dis. 2024 Oct;43(10):2053-2059. doi: 10.1007/s10096-024-04908-6. Epub 2024 Jul 31.

Abstract

A multicenter review of Periorbital Necrotizing Fasciitis including nine cases, aged 41 to 82, mostly female, and mainly post-traumatic or idiopathic. Streptococcus pyogenes was the most frequent pathogen. Treatment involved debridement alongside antibiotic therapy in all cases. Two cases experienced toxic shock, with no fatalities. Visual outcomes varied from exenteration to preserved visual acuity with minimal aesthetic impact. Early detection and prompt intervention are paramount due to the significant risks associated with this condition, which may lead to severe complications ranging from vision loss to systemic decline or death.

Keywords: Necrosis; Periorbital cellulitis; Periorbital necrotizing fasciitis; Periorbital necrotizing soft tissue infections; Streptococcus pyogenes.

Publication types

  • Case Reports
  • Multicenter Study

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Anti-Bacterial Agents* / therapeutic use
  • Debridement*
  • Fasciitis, Necrotizing* / drug therapy
  • Fasciitis, Necrotizing* / microbiology
  • Fasciitis, Necrotizing* / surgery
  • Female
  • Humans
  • Male
  • Middle Aged
  • Streptococcal Infections* / diagnosis
  • Streptococcal Infections* / drug therapy
  • Streptococcal Infections* / microbiology
  • Streptococcus pyogenes / isolation & purification
  • Treatment Outcome

Substances

  • Anti-Bacterial Agents